BIOSTATISTICS & RESEARCH METHODOLOGY - THEORY
1. Research Methodology : Introduction
a) Types of clinical study designs:
- Case studies
- observational studies
- interventional studies
b) Designing the methodology
c) Sample size determination and Power of a study
- Determination of sample size for simple comparative experiments,
- determination of sample size to obtain a confidence interval of specified width,
- power of a study
d) Report writing and presentation of data
2.1 Biostatistics :
a) Introduction
b) Types of data distribution
c) Measures describing the central tendency distributions:
- average,
- median,
- mode
d) Measurement of the spread of data-
- range,
- variation of mean,
- standard deviation,
- variance,
- coefficient of variation,
- standard error of mean.
2.2 Data graphics Construction and labeling of graphs:
- histogram,
- piecharts,
- scatter plots,
- semilogarthimic plots
2.3 Basics of testing hypothesis :
a) - Null hypothesis,
- level of significance,
- power of test,
- P value,
- statistical estimation of confidence intervals.
b) Level of significance (Parametric data):
- students t test (paired and unpaired),
- chi Square test,
- Analysis of Variance (one-way and two-way)
c) Level of significance (Non-parametric data):
- rank test,
- Wilcoxan rank sum test,
- Mann Whitney U test,
- Kruskal-Wall is test (one way ANOVA)
d) Linear regression and correlation- correlation and correlation co-efficient.
e) Introduction to statistical software:
2.4 Statistical methods in epidemiology
- Incidence and prevalence,
- relative risk, attributable risk
3. Computer applications in pharmacy
- Computer System in Hospital Pharmacy : Patterns of Computer use in Hospital Pharmacy Patient record database management, Medication order entry Drug labels and list Intravenous solution and admixture, patient medication profiles, Inventory control, Management report & Statistics.
- Computer In Community Pharmacy : Computerizing the Prescription Dispensing process Use of Computers for Pharmaceutical Care in community pharmacy Accounting and General ledger system
- Drug Information Retrieval & Storage : Introduction Advantages of Computerized Literature Retrieval Use of Computerized Retrieval
Reference books:
a. Pharmaceutical statistics- practical and clinical applications, Sanford Bolton 3rd edition, publisher Marcel Dekker Inc. NewYork.
b. Drug Information- A Guide for Pharmacists, Patrick M Malone, Karen L Kier, John E Stanovich , 3rd edition, McGraw Hill Publications 2006
Comments
Post a Comment